ITALY
Digital Imaging Multimodal Platform Neuromed - DIMP NEUROMED
The Digital Imaging Multimodal Platform Neuromed - DIMP NEUROMED is a single- sited, multimodal Node aiming to provide access to an integrated digital analysis support for preclinical and clinical studies in the field of neuroscience, extending from the study and evaluation of animal models to their translation into clinical practice. It is composed of a preclinical (Multimodal Molecular Imaging) and clinical (Population Imaging) access to imaging technologies and molecular probes, with dedicated computing systems for both clinical and preclinical data analysis. Data is collected with multimodal imaging and analyzed to extrapolate imaging features to quantitative parameters of clinical interest.
Users can perform their own preclinical and population studies using our facilities or can leverage our extensive expertise in both settings to design and perform multimodal experiments with cutting edge clinical and preclinical technologies and qualified operators.
A view of the NEUROMED campus
Specialties and expertise of the Node
Our preclinical facility is a complete mouse clinic with available technologies as 7T MRI system, micro-ultrasound system, micro-CT and Optical Imaging. Our mouse clinic is equipped with cutting-edge surgical platforms for mouse surgery aimed at establishing pathological models, a breeding facility to host transgenic colonies, behavioral phenotyping facilities and cardiocirculatory phenotyping facilities as radiotelemetry and tail-cuff based blood pressure measurements.
Our clinical facilities have been recently overhauled by a total renovation of MRI imaging system, with a newly-installed 3T MRI equipped with a 64-channel brain coil and a cardiac coil. MRI population imaging benefit from research-dedicated computing facilities, with all gold-standard neuroimaging software available (FSL, Freesurfer, AFNI, ANTs, SPM) and ad-hoc analysis pipeline development.
Offered Technologies
| Technologies | Euro-BioImaging |
| micro-MRI/MRS (>= 7T) | ✓ |
| micro-CT | ✓ |
| in vivo Optical Imaging | ✓ |
| micro-US | ✓ |
| micro-MRI/MRS (>= 7T) - ex-vivo | ✓ |
| micro-CT - ex-vivo | ✓ |
| Image Analysis-med * | ✓ |
| population imaging (PI) | ✓ |
| Laser Scanning Confocal Microscopy (LSCM/CLSM) | ✓ |
| Two-photon microscopy (2P) | ✓ |
| Multiplexing Imaging (MXI) * | ✓ |
| Intravital microscopy (IVM-med) | ✓ |
Additional services offered by the Node
- Project planning and methodological setup
- Mouse clinic and animal breeding facility
- Wet labs
- Cell culture facilities
- Chemistry and radiochemistry labs
- Biobanking
- Data processing and analysis
- Data storage
A view of the Bio Bank for Population Imaging studies
Contact details
Administrative coordinator:
Dr. Massimo Pillarella
dimp@neuromed.it
Scientific coordinator:
Dr. Lorenzo Carnevale
lorenzo.carnevale@neuromed.it